A new superbug competes with MRSA for dubious top honors PDF Print E-mail

Clostridium difficileThe steady hum of the florescent lights did nothing to dim the chirps and beeps of the array of equipment surrounding the seemingly immense bed.  A small, fragile figure appears to sleep peacefully despite the battle being waged inside her 84 year old body.  The doctor asks Samantha to step out into the hall for a moment, a concerned look on her face.  "I'm afraid your mother has contracted C. diff," the doctor says with as much empathy as she can muster after another horrendous shift.  Samantha's face quickly reflects a state of puzzlement, "What in the world is C. diff, my mom is just here because of a broken hip."  The doctor quickly explains that C. diff is a type of bacteria that is attacking her mom from the inside.  "We are doing everything we can, but I am sorry to tell you that your mother doesn't have much time."

The previous scene is getting played out more and more frequently.  C. diff, Clostridium difficile, was typically confined to older patients in hospitals and residents in nursing homes; associated with diarrhea that responded well to conventional treatments.  Unfortunately, C. diff has evolved into a form that is highly resistant to even today's most powerful antibiotics.  The newer, more virulent strain of C. diff is referred to as NAP1 which produces roughly 20 times the toxins as the normal strain, overwhelming the body's immune system.  This strain can cause illnesses which range from simple diarrhea to colitis to sepsis (blood poisoning) and even death.

Toxic strain probably in your state already 

According to the Centers for Disease Control, the most toxic strain of C. diff is becoming more widespread.  38 states have confirmed cases of C. difficile-associated disease (CDAD) with the mutant NAP1 strain:

C.Diff State Map

What is troubling scientists and doctors even more are the cases of CDAD involving younger, healthier individuals.  A study published in the Morbidity and Mortality Weekly Report (MMWR), relayed several cases of patients with CDAD that resulted in extended hospital stays and even death.  In one case, a 31 year old pregnant women contracted CDAD.  She spent nearly a month in the hospital over two extended stays and tragically died along with her unborn children.  Fortunately, not every case has such a horrendous ending.  A ten year old girl was taken to the hospital in severe abdominal distress.  She responded well to treatment after being admitted through IV fluids, electrolytes and a powerful antibiotic.

CDAD occurring with greater frequency 

The number of cases of CDAD is also increasing rapidly.  The CDC reported that infections resulting from C. diff more than doubled between 2000 and 2005.  Over 300,000 cases of CDAD were reported in 2005 according to hospital discharge records with almost 29,000 people dying that contracted the illness.  Recognizing that many cases go unreported and the statistics do not include long-term care facilities, the total number of people that contracted CDAD is certainly higher. The C. diff bacteria produce anaerobic spores that can survive for several months on most common surfaces.  The infection is spread when people ingest the bacteria after touching a contaminated item or food.  The bacteria has been found in hospital room bed rails, telephones, blood pressure cuffs, tabletops, curtains and other surfaces of infected patients.  Healthcare workers caring for an infected patient, pick up the spores on their hands, and inadvertently spread them to other patients.  Unless stringent infection control practices are followed, the C. diff spores can remain in the room, waiting to infect the next patient.

Fighting the battle

Making the fight against C. diff even more difficult, common hospital germicides and the ubiquitous Purell-like alcohol hand sanitizers don’t kill C. diff, experts have stated. To eliminate it from surfaces a bleach solution is necessary.  Good old hand washing is also effective due to the friction.

The best way to combat C. diff is to prevent it.  The following practices should be considered when attempting to avoid C. diff and other similar bacteria in a hospital setting:

  • Frequent hand washing using soap and water.  Remember, alcohol hand sanitizers don't kill C. diff.  Use common sense, wash your hands before meals, after using the bathroom and touching common surfaces
  • Don't be afraid to demand that your visitors and health care workers practice proper hand washing as well
  • Although it may seem excessive, you may want to bring your own 1-to-10 solution of chlorine bleach to clean common surfaces like your bedrails, phone, door handles, etc.
  • Health care workers should be using fresh gloves when they enter your room as well as gowns 
  • Ensure you receive clean gowns and other clothing for yourself as well as daily bathing

In the unfortunate situation CDAD is contracted, antibiotic treatment may be required with metronidazole or vancomycin.  In serious cases, intravenous medications or surgery may be necessary.

Remain GermAware 

Obviously the ideal situation for everyone is to remain healthy and avoid C. diff.  Remaining GermAware when faced with superbugs like C. diff and MRSA is only common sense.  Take the time to remain educated, healthy and prepared.  It may make a difference for you, your family and friends.



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Comments (61)add
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written by bev , June 05, 2008
i also contracted c-diff, i was sick with this for already 2 months. still i am not at my best. i am a 46 year old woman who works in a nursing home, who got it from a resident. i was severly dehydrated, the diarreha was the worst of anything. i relapsed 3 times, now i hope i am on the oad to recovery. i hope nobody ever ges c-diff.
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written by lynn , June 10, 2008
I know someone with cdiff she works with the elderly is it safe for her to be working there she is on antibiotics and she claims the nurse told her she could work, is this true. smilies/cool.gif
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written by Sue , June 20, 2008
I have just been diagnosed with c.diff after taking antibiotics. The diarrhea is horrible and the cramping is the worst! I'm having a hard time working but I've only been on meds for 5 days so far. I pray that I don't have a relapse as once is enough already! Sounds like I should worry about passing it on to my boyfriend. Glad there are precautions listed
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written by dthomas , June 20, 2008
If you do contract c. diff, it is critical to practice basic infection control techniques with the expanded use of a 1-to-10 bleach solution. Remember, c.diff is not killed by alchohol. Getting c. diff after taking antibiotics does happen as the antibiotics kill off the some of the "flora" which typically keeps c. diff in check. Make sure you wash your hands completely and clean any suspect areas like bathrooms with the bleach based cleaners. Hope you feel well soon.
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written by agraham , July 04, 2008
I would like everyone to be aware that when you visit patients in the hospital with diarrhea, YOU SHOULD TREAT EACH PERSON AS IF THEY MIGHT HAVE C.DIFF. because the staff might not. My mother was admitted to her local hospital and EVEN AFTER TELLING US WHAT SHE HAD - THEY DID NOT PLACE MY MOTHER IN ISOLATION OR TELL US TO WASH OUR HANDS. We do have some family that work in the hospital and they told us. Our family was also the one to tell us to disinfect her bathroom and bedroom and kitchen where she had had many accidents. Bottom line to me - Learn more and protect yourself.
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written by GermAware , July 07, 2008
Thanks agraham, very well said. With the increasing cases of C. diff, you are better off assuming the person may have C. diff vs. suffering the possible consequences. BTW, it is atrocious that the hospital did not place your mother in isolation after she had C. diff. I have spoken to local hospital staff and in my area if a person has C. diff they are immediately placed in isolation. Once the person has been discharged, the room is cleaned from top to bottom.
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written by Cindy , July 12, 2008
I was diagnosed with C diff years ago. Being into alternative medicine,I refused the normal treatment. I began taking Jordan Rubin's Primal Defense (PD). Increasing by one each day until I reached 12 daily. In one month, I had severe diarrhea, but being aware of Herxheimer Reaction, I knew I was killing the bacteria and they were dying off, so I endured the dizziness, nausea, headaches and achiness. Increased water and fiber. Continued on PD for three more months, but was retested after the first month. No C diff., and I felt great and gained my weight back after a few months. Hope this helps someone.

PS About a year after choosing to NOT take the Flagyl and taking PD instead, I researched where Flagyl causes cancer. I always pray about what I need to do first. You have to be a thinking person and research (and cross reference and get with those who understand alternative medicine) if you are to be well in this day and time.
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written by mavs , July 20, 2008
im working in the retirement home but my resident return from the nursing home had a c diff.it is safe forme to work this resident that now im pregnant? i always wash my hands and use gloves before entering her room.
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written by Pamela , July 24, 2008
I am working in a private home with a person who has c-diff all of us are using gloves and wipe evrything down with the bleach solution, but what should we be doing with the soiled briefs? also body fluids have gotten on carpet, would a steam cleaner kill the spores? any tips on proper care would be appreciated.
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written by Mary , July 28, 2008
My Mom was just admitted to the hospital with c diff after 2 weeks in nursing home, and 2 weeks in hospital prior to that...I have cleaned my Moms bath and bedroom surfaces with bleach and water sol...I have washed her bedding and clothes with 1/4 cup bleach added to each wash...what else should I be doing?

(She has alzheimers, so reminding her to wash w/soap and water after toileting is challenging!)
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written by Chrystal , July 28, 2008
My 86 year old mother had c-diff so bad we thought we were going to lose her she made it home from the hospital only to get the c-diff back after 6 weeks,she is now in the hospital so weak an i sick I hope she can make it home again,but i'm so afraid she will get the super bug back again.........aloha,Chrytsal
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written by joanne , July 29, 2008
My husband contracted c diff when he was in the hospital to have the whipple procedure for pancreatic cancer. never having had surgery before we assumed that the symptoms were due to the surgery. He took the flagyl and it cleared but 3 weeks later he was back in again with c diff. The hospital doesn't consider the drug a failure until it has failed 3 times. We live in terror of this happening again. This time it seems to be affecting him more. Maybe that is just us. He is much sicker this time. It scares me to read that flagyl causes cancer.
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written by joanne , July 29, 2008
I forgot to say that while we were there we saw a man who had the whipple 2 days before my husband and he was back in again with you guessed it c diff. I noticed that the cleaning practices and the isolation practices were sadly lacking in the hospital and worried me tremendously.
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written by WENDY CAMPBELL-PEEK , July 30, 2008
MY SON IS IN HOSPITAL AND HAS CAUGHT C. DIFF. AS YET HIS ROOM HAS NOT BEEN CLEANED ONCE SINCE HE HAS BEEN IN THERE. AFTER READIN ABOUT THIS C.DIFF. I WILL BE GOING INTO THE HOSPITAL TODAY WITH A LOT OF QUESTIONS THAT I WANT ANSWERED. THANK YOU VERY MUCH FOR THIS INFORMATION.
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written by Linda Mazza , August 10, 2008
My 93 yr old father has been ill for 7 weeks and was diagnosed with C-Diff three weeks ago. Hospital practices were good, but I don't know if they were using bleach solution each day to clean it. We were told to wear gloves and wash our hands before leaving and a gown for hugs. The trouble is he still has a raging case of C-Diff but hospital sent him to a rehab unit in our hometown and this place is absolutely not practicing good prevention. They did not isolate him the first day and did not provide gloves til I demanded that they do so. Also, staff is not wearing gloves or washing their hands after handling things my Dad is handling. I am terribly frightened for him and for all of us who visit because of their lack of bleaching, etc. The hospital sent him on to this place when he is still very sick and has terrible diarrhea that is constant. He needs prostate surgery but cannot get it due to illness with C-Diff. I think I need to go in to this place tomorrow armed with what I now know demanding better cleaning methods and protection for employees.
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written by Kellie , August 21, 2008
My dad caught c.difficile after having back surgery. He was extremely sick with it and after he came home from hospital my mother got it. Now she is very sick. The hospital my dad stayed at was pitiful. The didnt clean him, his bathroom, and his papers that was sent home with him had he had back problems. Im mad at the hospital he contracted this disease and im mad that the hospital down the road didnt take good care of my dad and my mom had to clean up after my dad and I think thats why she has it now.
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written by michelle jones August 23 , 2008 , August 23, 2008
My mother is currently on life support fighting for her life , she was diagnosed with c diff while in coronary care 2 weeks ago .Through out the whole time of diagnosis she was not isolated and we were never told to wash our hands or wear gloves and aprons , after immense suffering she was rushed for emergency surgery as she was dying , this has been the most horrific thing l have ever experienced , l have had to gain all of my information from the internet. My mother has been in hospital since the 11th may for major heart surgery , and while visiting her we have never and l mean never seen a cleaner in the hospital , never witnessed a doctor or nurse washing their hands , and not once have we smelt the hospital smell that we used to years ago as soon as you walk through the door ( disinfectent , bleach ) these superbugs will not go away if its left to the NHS
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written by teresa , August 30, 2008
My mother was admitted at Humber River Regional Hospital on June 16, 08. She was in a nursing home and upon admission to hospital we were advised she had C difficile. She was not placed in isolation while in the emergency ward. On June 17, 08 she was taken to the floor. When we visited on the 17th the nurse was not able to even get a blood pressure reading on her, but there was no concern on the nurses part. We left that evening at 9:30 pm. I called the hospital at 10:30 and the nurse told me she was able to get a BP reading but was still working on her chart. At 3:30 am on June 18 08, I received a call that Mom was in grave condition. By the time we got to the hospital she had died. She was never in isolation, she wasn't even on IV antibiotics, no wonder C-dif killed her.

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written by Jacenda , September 07, 2008
I have contracted cdif and have had it for four months. I had it for 3 months and almost died with it because my doctor would not listen to me. and now I believe it is to late and the damage is irreversible. All be cause my doctor would not listen to me. If any of you have a doctor that want listen to every single word or complaint that you have and only assumes this and that live them and find another doctor. This is so sad that people have grown so lazy that the jobs that we pay them to do they don't. I weighed a 158lbs. before I got cdif and I have lost over 20 pounds. I am so sorry for all that is sick and in pain and I wished there was something I could do to help because sometimes it seems that praying isn't enough. I sit and and wonder where we are falling short at.
if anyone would like to email me feel free at This e-mail address is being protected from spambots. You need JavaScript enabled to view it '> This e-mail address is being protected from spambots. You need JavaScript enabled to view it

Sincerely Yours: Jacenda
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written by JANET , October 01, 2008
My 91 year old nan went into hospital 2 weeks ago with numoania,(sorry about the spelling) she passed away this morning at 3.15am I dont know what caused her death yet but 2 days ago they said she had an infection, we found out yesterday that the name of the infection was cedif, I know they were treating my nan with antibiotics, the hospital left my nan in her own mess because they only had 4 nurses on duty, it was a couple of days before they had us wearing a gown and mask to vist her, she was in a ward with 5 other elderly women, they had to put up with the smell of my nan lying in her own mess and all have been put at risk of contracting this infection them selves, I think it is awfull how people are treat in hospital these days especially the elderly, my nan was in alot of pain and discomfort right to the end, something should be done about all the infections in hospitals before it really gets out of hand, familys are not being told early enough about the infections that there loved ones have, you visit, go home and help spread the infections around where will it end. GOD BLESS YOU NAN x
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written by Lori , October 06, 2008
My mom age 68 has cdiff, and I relate to all of the above comments. This has just happened and we are living in a nightmare. PLEASE help me by answering the following-- How do I make the guestroom and bathroom safe again for others? Do I throw away all that I can not bleach? The same with her clothes? Do we have to wear the gowns as well as the gloves when visiting? Tell me all that you can and God Bless You!
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written by herb , October 08, 2008
I had a severe case of c diff last year and was in isolation for a week. In addition to vancomycin and flagyl I took Florastor and Saccromydes Boulardi (the latter prescribed by my doctor). Both of those are available over the counter on on the internet, and based on my research are likely to help and non toxic - unless you have a fungal infection in which case you should not take Boulardii. I recovered in about two weeks, though I was weak for at least three months. I will take these probiotics the rest of my life and avoid antibiotics unless I truly have a life threatening need for them.
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written by Bob , October 19, 2008
THANKS!! to all who have posted info and comments here, I have learned even more reading them. I was just diagnosed with C. diff this past Mon. at my local ER. I'm now 56 and until 2001 after having bypass surgery have been pretty healthy, or as my friend says, "I'm in pretty good shape for the shape I'm in". He says this because of my long standy history of post spinal surgery X 4 after becoming parylized from neck down in USAF Jan 1980-Dec 1981 relived by 4 surgeries.
In ealy 2001 after years of trying to get Veterans Drs to listen to me I hadthe bypass surgery on my left Aorta feeding my left leg. Soon after was misdiagnosed with Viral infection and finally diagnosed with bacterial infection and treated with Vancomycin. Although relived I've never felt it was eliminated. Now after numerous years of recurring symtoms and bad flareup I'm now on Flagyl and without a doubt, scared as HECK!! I am planning to research HERBAL treatments as I agree I don't think the conventional chemical meds is the answer.. I was impressed to read in your article that Coloidal Silver was a good choice and I believe in CS as I was told it is a natural antibiotic and when I used it years ago it was amazing. I'm planning to get some again..
THANK all of you so much for your input..
Respectfully
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written by Linda in San Diego , October 30, 2008
My mother, who is 77 years old, got pneumonia, then cdif, then colitis. She was in ICU for months. Many times she almost died, she left the hospital with a tracheotomy. She is fine now. (she was in the hospital or my home when she contacted the cdif). My father, 81 years old, had heart surgery, which developed into a leg infection, which lead to a broken hip, then pneumonia and now Cdif. (from the care facility) He wants to die. While the hospital (same one as my mother) has taken GREAT precautions to stop the spread, the residential care home my father was in, was limited to gloves, no isolation, no gowns, etc. My father is in the hospital now and does not even want to leave the bed. But the hospital wants to send him back to a care facility. I think the hardest thing about Cdif is that it makes people so weak that they quit fighting. My father does not want to eat or anything. I will spend today trying to find a care facility that will help.
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written by Linda in San Diego , October 30, 2008
Signs of Cdif***smelly diarrhea***very easy to happen after antibiotics, I think that if you practice good hygiene you will probably not get the cdif unless you are on antibiotics or have problems with your immune system.
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written by BelindaK , November 19, 2008
I was put in the hospital with c. diff. in August. Not only did they not place me in isolation, they gave me a roommate with MRSA and did nothing to protect either of us. 3 1/2 months later, I still have it. I keep getting various infections that require antibiotics. As soon as I start taking them, the c. diff. comes right back. This is really serious stuff. You must protect yourself. The hospital certainly isn't going to do it.
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written by charlotte , November 23, 2008
I have had this c-d for about the fifth time this year. I have had to take the fagel each time. Now I have had to double up and take it longer to make sure I get rid of the germ. The dr. said this strain was not contagious but I wonder now after reading the comments about this. I have two granddaughters and I am with them all the time. I am clean with washing and keeping the bathrooms clean. But is it possible they could get it too ? One granddaughter is sick at this time with what they think is a virus. She doesn't have direhea though.
It would break my heart if that happened because of me.
So anyone have any advice on this please write to me.

This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Thank you,
Charlotte


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written by dorothy , December 03, 2008
My son is in a nursing home for end stage of congestive heart failure Whle there, I was informed three weeks ago that he had cdiff. I did not know what cdiff is. How did he get it. No one at the nursing h ome will teel me anything about how he got it. During the three week period he has lost much weight because he does not want to eat. He is 50 years old. Is there anything I can do to help. I was just told that the doctor recommended he be put on Flagyl. After reading the above, I see it could cause cancer. No one shared this information with me. Can anyone help with recommendations to get rid of this, herbal or over the counter. If you would please send me some information, I would certainly appreciate it.
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written by amy , December 16, 2008
my dad passed sunday morning--he spent 3 months fighting for his life. he went into hospital after a fall which broke his hip and elbow. surgery went great and went into nursing home for rehab which was suppossed to be for a few weeks. just a few days before discharge he came down with a horrible diarrhea which carried a distinct oder and a fever and dementia. it took a week before any attention was given or testing for c-diff was done... from there he became septic due to the toxins flowing through his body. he entered emergency and critical care where he stayed for 2 weeks...this story goes on and as i said the ending is tragic. please be vigilent in monitoring your loved ones. we always had some family member there to visit and help him out during his stay at rehab, yet even when we all told the nursing staff and doctors that he was getting sicker and sicker it took too long to treat him properly and his whole colon was just too infected to save. make your doctors listen to you and do as much research on this c-diff problem as you can. smilies/angry.gif
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written by Hua Kul , December 29, 2008
Part I (NOTE: I was unable to post this entire comment so I broke it up into parts)

After my wife's third bout of C. diff. it was coming back a fourth time when she started taking calcium disodium EDTA 500mg twice per day. The diarrhea never returned and the characteristic C. diff. smell of her feces went away after two weeks. The research I did leads me to believe that EDTA works by chelating manganese and calcium, which are both necessary for the toxins to permeate and break open gut wall cells. The contents of the broken cells is the food source for the C. diff. bacteria and since the toxins can't break open the cells I believe the bacteria starve to death. Below I have copied a synopsis of our experince, which I had shared with a Canadian news reporter who had done a series of articles on C. diff.

--Hua Kul


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written by Hua Kul , December 29, 2008
Part II

You mention that you saw some clues in the supplement that made you think it might be helpful to your wife. What were they...?



One thing I realized was that the symptoms and damage from C. diff. are not caused by the bacteria itself but by chemical toxins that it produces. The next logical thought was that if the toxins can be neutralized then there would be no symptoms even if the C. diff. bacteria thrived for the six months or so that it takes to rebuild the normal gut flora. I had started taking oral EDTA about two months previously because I have some arterial calcium (indicating plaque in my coronary arteries) and EDTA is sold in the U.S. as an oral supplement for the purpose of reducing arterial plaque (it's effectiveness for that is debated). After learning about EDTA I decided to try it for the health of my arteries. In the course of reading about it I read the following paragraph:

"Calcium disodium EDTA will chelate toxic heavy metals within the gastrointestinal tract. Unabsorbed calcium disodium EDTA (the portion that doesn’t make it into the bloodstream) continues to chelate toxins as it passes through the body. It does a great job of cleansing bile acids of toxins which keeps them from being reabsorbed into the body. Toxins in bile are believed to play a prominent role in the development of colon cancer. So, even unabsorbed calcium disodium EDTA contributes to overall general health."
http://www.smart-publications.com/heart_attacks/business_of_chelation.php

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written by Hua Kul , December 29, 2008
I then started looking for anything indicating EDTA may also neutralize the C. diff. toxins, which might make it useful for my wife. I found the following paper which shows that EDTA neutralizes the toxins from Clostridium perfringens.

“The alpha-toxin of Clostridium perfringens, a lecithinase (phospholipase C, EC 3.1.4.3), is important in initiating the lethal process of gas-gangrene (11). Its in vitro activity is enhanced by certain metal ions and inhibited by metal-binding agents (10). Various metal-binding compounds have been investigated as possible in vivo therapeutic agents, and the chelating agent, ethylenediaminetetraacetic acid (EDTA), protected animals against the toxin alone or experimental gas gangrene (3, 4, 13, 14).”
http://www.pubmedcentral.nih.gov/picrender.fcgi?artid=249899&blobtype=pdf

Clostridium perfringens is the bacteria that causes gas gangrene, but since it's related to cdiff I thought there just might be a chance that EDTA would also neutralize the C. diff. toxins. To make a long story short, at the end of her third round of antibiotic the C. diff. appeared to be returning. We did not go back to the doctor but she immediately started taking EDTA on the chance that it might work. That's why I called it an experiment, we had no knowledge at the time that it would be of any help, just theory. There was no danger, as EDTA is very safe even in large doses, and if it didn't work we would just return to the doctor for a fourth round of antibiotic or some other treatment such as a fecal transplant. The C. diff. symptoms receded within a day. My wife has been taking 500mg twice per day and at this point there is no more occurrence of any C. diff. symptoms. This is more than two months past the end of her antibiotic. She wants to continue taking it for awhile just to make sure everything stays OK. This, of course, doesn't prove that the EDTA works. One clue that the EDTA is working is that, when my wife would miss her second dose for 2-3 days in a row the unmistakable C. diff. smell returned in her feces, but when the correct dose was resumed the smell went away within 1-2 days. This happened a couple of times in the first six weeks of use.

--Hua Kul
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written by Hua Kul , December 29, 2008
Part IV

...is the drug sold over the counter in the United States? You mention that it is inexpensive – what does it typically cost?



Yes, it is available OTC. The capsules I buy each contain 250mg calcium disodium EDTA, 300mg malic acid (from apple cider vinegar), and 100mg of garlic. A bottle of 120 costs US$34.95. That's a 30-day supply at the dose my wife takes. Here is my source, http://www.hfn-usa.com/product...dio_Health



Do you know of anyone else using this therapy...?



No.



...have you received any feedback on it at all from your wife’s doctor?



He doesn't even know about it. Since it seemed to be working she hasn't gone back to him, and in the past he's been very resistant to any talk of any kinds of alternative treatments for anything so I didn't want to antagonize him.



As far as I know no one has ever used this treatment. When it seemed to be working I searched the literature for indications of the specific reasons why it should work, and in the end came up with what I think is the mechanism behind it.


--Hua Kul


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written by Hua Kul , December 29, 2008
Part V

1. The toxins are not randomly produced but are meant to provide food for the C. diff. bacteria by breaking open gut wall cells.

http://www.sciencedaily.com/releases/2007/09/070905095328.htm



2. Calcium is necessary for the toxins to break down the gut wall cells.

http://ajpgi.physiology.org/cgi/content/abstract/268/3/G487



3. Manganese is also necessary for the toxins to invade the cells.

http://jmm.sgmjournals.org/cgi/content/full/57/6/690

http://www.jbc.org/cgi/reprint/273/26/16021.pdf



4. EDTA chelates both calcium and manganese.

http://books.google.com/books?id=8pViePEG27sC&pg=PA133&lpg=PA133&dq=edta+manganese&source=web&ots=NNfTJc0jbz&sig=kI-pqLjvmpf13hTPxMl_Vw4f-kk&hl=en&sa=X&oi=book_result&resnum=1&ct=result#PPA132,M1

===================================================

God Bless,
--Hua Kul

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written by Hua Kul , December 30, 2008
(The final part of my post didn't post, the message said Waiting for Admin Approval)
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written by mona , January 02, 2009
I could not find anything about what kind of diet is good for c.diff and how we
have to stick to it?
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written by Vicki , January 20, 2009
My Mother had a pace maker implanted and contracted MRSA in a hospital in Pa.. She almost died, having to have pacemaker removed and implanted on the opposite side. She almost died again! She has since went to Ohio to live with my sister and was admitted to hospital there after falling and getting 3 broken ribs, she has contracted C diff NOW! She had her big toe removed to gang greene, she is in total body pain from this C diff! WE PRAY SHE WILL MAKE IT!!! Where is the media when its important to everyones LIFE!!
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written by Margot-San Diego , February 17, 2009
I am a RN, and had a question from a family whose loved one is going home to their house, and she has C. Diff. What do you use to clean the carpet when there has been an "accident?" Bleach products would wreck it. The same for colored clothes....adding bleach wouldn't work. Any suggestions for these items?
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written by brenda macdowell , March 08, 2009
my mother recently died from c.diff. i learned about saccharomyces boulardii ( sold under the brand name florastor)too late to help my mother. A recent meta- analasis of 31 studies compiled and published in the American Journal of Gastroenterology concluded that S. boulardii is the only probiotic that is effective in fighting recurrent c.diff-associated desease. It is mentioned by the World Health Organization for use in the management of c.diff-associated desease.
Lactobacillus GG (sold under the brand name Culturelle) has also been effective. This probiotic replaces the good bacteria tha antibiotics kill and prevents c.diff from attacking the intestinal walls. please look into these probiotics for yourself and learn how you can prevent loved ones from c.diff and share the information.
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written by marie , March 17, 2009
my son is 18 months old and he has cdiff. he has had it for about 2 months and he will be starting his second round of medication. wer asked the doctor to addmitt him be she won't because he is not dehydrated. i don't care i ust want it to go away.
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written by Sue , March 18, 2009
Reading some of the stories posted on this forum are really heartbreaking. There is so much lack of knowledge--even by professionals. I recently sent a link to this page and my story to a Pittsburgh TV station begging them to research C. Diff. and start reporting on it. I came down with a UTI on Feb. 17 and was hospitalized. I was given 3 antibiotics, one was Clindamycin. Next I got colitis and was re-admitted. All antibiotics were stopped, but no one tested me for C. Diff. I probably had it then and was in a room with another patient without it for 4 days. I improved and was sent home and a week later got worse and was diagnosed with C. Diff. after I asked to be tested. Over a week later now I am recovering on Vancomycin. Flagyl made me ill--mental confusion, nervousness, total lack of appetite. But no one even told me C. Diff. was contagious and you can re-infect yourself or others. Glad I researched it myself on line immediately. I insisted on staying home fearing re-infection in the hospital. But it is a lot of work to do when you are ill--washing clothes in hot water is sufficient, everything else in question in my home gets cleaned with a 1:10 bleach solution and nothing leaves my bathroom but the garbage or items going directly to the washer. I wash my hands for 15 seconds repeatedly and in some cases sprayed my hands with the bleach solution. I have not had any carpet issues, but I would have seriously considered cutting it out. Carpet is replaceable, lives are not. I hope and pray I have done enough to rid my home of this bacteria. I just ordered some Florastor also. I was able to leave my house 2 days ago finally, but after 5 weeks of all this I am worn out. One question I have, my doctor said to avoid milk. Does anyone know if there is a reason for this as far C. Diff. is concerned?
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I was just told I too have c.diff. Now I am really scared that my grandson will get it. I have put all of his toys in a clorox mix. I have cleaned my house with clorox mix until my hands are sore will this prevent him from getting it. I am on my second round of Flagyl. The first time was for 10 days twice a day now it is 15 days 3 times a day. I have been told that we all have this in our body but it takes using antibotics to bring it on is this true. Please let me know how safe is my grandson.
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written by Marcus , April 13, 2009
Hello,

My name is Marcus and I am graduating senior from Howard University. I am 22 yrs old and I was diagnosed with c.diff 5 months ago. Im really scared and confused about what to do about treatment. Ive been on flagyl and vancomysin only to relapse for the 4th time. Why as a health male, do I have a infection of this magnitude?...I really am tired of having diahrrea and the abdominal cramping. Also from my colonoscopy I have hemrroids from the strain of having diahrrea. Im really concerned about my life and I dont kno wat to do next?...If anyone has any advice could you please email me @ This e-mail address is being protected from spambots. You need JavaScript enabled to view it '> This e-mail address is being protected from spambots. You need JavaScript enabled to view it

Thank You so Much, and God Bless

Marcus
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written by Linda , April 22, 2009
This cdif is so depressing. My father HAS IT AGAIN (I posted months ago). The nursing home just gives up. There is little I can do, because I changed nursing homes and now realize they are more the problem then the solution. I have been buying him proibotics, it has not worked. I am going to try the Florster next. This is a nightmare and the medical community is NOT helping.
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written by Tiffany , August 16, 2009
My grandmother died this morning. She contracted C. Diff. She came down with colitis, then sepsis and ultimately death.
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written by Angela , March 20, 2011
I am 41 mother of 4 (including twins) and I was diagnosed with C-diff on March 2, 2011 in the ER after having what I thought was the flu. I have not been on any antibotic for a year or more, nor that I know of been around someone with c-diff. I am still battling my c-diff and I hope that I can help others with this terrible disease. When I came home from the hospital I was using Clorox wipes, Clorox cleanups, Clorox 2 & Bleach, everything the nurses told me to use -- so I contacted Clorox to get coupons and I was informed by the Clorox company that everything I was doing was wrong.

To kill the C-diff you have to use Commercial Clorox Germicidal Bleach and it has to state on the container that it kills Clostridium difficile spores, it is sold only at home improvement stores like Lowes it cost around $3.50 for 1.42 gallon jug.

I hope this helps everyone out there that like me was doing everything wrong to fight back at this horrible disease.
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written by Patti , September 06, 2011
I have just been diagnosed with this terribly painful condition, after visiting my mom at the hospital. My grand daughter and great granddaughter have all been exposed as well. I am very concerned about them. I am taking Flagyl at the time and have contacted them to see a Dr.as soon as they get any symptoms. The pain in my left side is so bad and bloated that I feel I am about to burst. Very scary.

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written by BartonVonda24 , April 04, 2012
If you want to buy real estate, you will have to receive the credit loans. Moreover, my brother commonly utilizes a small business loan, which is really reliable.
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written by mulberry outlet , September 25, 2012
qgfmda Christmas is probably the most special day of the year for children. One thing that makes it special is the popular tradition of Santa Claus. ,mulberry outlet www.mulberryoutletshop.me.uk 177444
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I was diagnost with c diff. Very severe. It's in my colon. I've been in bed for 2 weeks now. And I went to emergency 5 times. The stomach pain is unbearable. I've list 10 lb
Anyone else with severe stomach pain? All the comments I read say diarrhea so I was wondering why I have the pain. I'm 39 years old. And I've been put on antibiotics atleaste 5 times a year between my doc. and my dentist. It seems like every little thing wrong with me they put me on antibiotics. I've nonentities on flagil for a week now. Feeling better but I'm scared I'm going to keep getting it or give it to my family. Is it highly contagious? Thanks for all the comments.
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written by Kendall , June 06, 2013
For hemorrhoids, use butcher's broom to make a tea. I read a post about it from a naturopathic doctor. She recommends soaking a cotton ball in the tea and inserting into the rectum overnight. She said that bulk Butcher's Broom is usually the most potent but you can also use the capsules which are available at health food stores. You can purchase the bulk butcher's broom from Starwest Botanicals on the internet. Taking Citrus Biflavenoids is also effective but you need to take six or eight of them a day. I buy the Twinlabs brand from Amazon. It is also helpful to put ice on them to shrink the swelling. I also like to use witch hazel to clean after every bowel movement. It is an astringent and helps shrink blood vessels and keep the area clean.
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written by lindylou , August 23, 2013
after 90 days of diahrrea day and night sometimes 20 to 30 times a day and every test under sun one test came back positive for c diff - doctor started me on flagl thinking I might have parasite going around in Iowa and Nebraska 2 weeks ago
and since positive for c.diff started on same medicine second time. I am 5'2" and have lost to 98 lbs am so tired and exhausted from day and night in bathroom(sometimes not making it) ugh!!! my question and one I ask doctor if it didn't kill it two weeks ago is it going to kill it now ---someone please answer. THANK YOU VERY MUCH



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written by Annie , October 16, 2013
Even though Flagyl, and Vancomycin treat c diff, they also kill the good bacteria. These can't be taken without a tremendous amount of probiotics, thus the relapses. Feeling better for awhile, then it comes back. That's because it can without good bacteria. I had this a long time ago when my front teeth were capped. I was very sick for a few months, and couldn't work. I used to cry from the pain on the commode. It felt like knives were in there! I never saw a doctor. I treated myself. I researched, and I started making my own pure oil of oregano capsules, and I took a good probiotic, I don't remember the exact one, and I think I took a couple thousand milligrams of vitamin C per day. I had only one relapse. I continued with the treatment when there was a relapse. It is horrible the way the medical establishment is pushing antibiotics like they do. I was shocked to read even for a uti, and three of them. All you have to do if it's not in the kidneys is eat a handful of fresh raspberries, blackberries, and some fresh (it's not that bad) cranberries everyday for only a few dsys, and drink plenty of water. Ohmygosh, the thought of getting c diff over a uti is wretched. I don't understand the zoned out thing about the medical establishment concerning using nutrition, and not actually causing illness, curing it. Also, don't ever take clindamycin. Ask for a different antibiotic if you must take one. It is well known for causing c diff. Another idea is taking bentonite clay to take that c diff right out! Research first though because I only know that you need to drink plenty of water, and also replenish minerals by taking supplements, because it takes everything out that could be bad, toxins, metals, parasite, bacteria, and the electrolytes are metal. Also there's a treatment just becoming popular called Fecal transfer. It is gross, but gets rid of c diff quickly, and restores health. With the massive amount of cases, they are finally learning that probiotics are needed when taking antibiotics. Just as CoQ10 should be taken with statins, and so many other facts that are not paid attention to because first there has to be tons of suffering. I just don't understand. I really feel for everyone who suffers from this, and other illnesses that did not have to come about. The Lord bless you.
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written by Annie , October 16, 2013
And I forgot to say plenty of fiber is important. Fiber is like a broom in the intestines. A relapse starts because if just one spore is left behind, hiding in one of the folds of the intestines, and there is no balance of good bacteria, it comes back. Probiotics are a necessity. Even if it feels like it's not doing anything, it is. Just take more. The good flora must be there to get better. Another thing, if someone is on acid blockers (tums and antiacids are alright) like prevacid, ect, this is the first line of defense. The stomach acid helps to kill pathogens. The older we get, the less we make. The elderly, as long as they don't still have acid problems, should get off of the acid blockers. This is like letting it through the front door. This is our immune system. It has to stay strong to keep us well.
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written by Annie , October 16, 2013
Sorry, one more post. I just saw this tonight, and the reviews are terrific. People are saying that after having to take antibiotic, especially alot of them, this is really helping to restore their health. Also, here is a list that I saw on another blog. Which antibiotics cause C. difficile colitis?

Although the antibiotic clindamycin (Cleocin) has been widely recognized as causing C. difficile colitis, many commonly prescribed antibiotics also cause colitis. Examples of antibiotics that frequently cause C. difficile colitis include:

* ampicillin,

* amoxicillin, and

* cephalosporins [such as cephalexin (Keflex)].

Antibiotics that occasionally cause C. difficile colitis include:

* penicillin,

* erythromycin,

* trimethoprim, and
* quinolones such as ciprofloxacin (Cipro).

Antibiotics that rarely if ever cause C. difficile colitis include:

* tetracycline,

* metronidazole (Flagyl),

* vancomycin (Vancocin), and

* aminoglycosides [such as gentamicin (Garamycin)].
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written by Annie , October 16, 2013
Sorry, here's the link that I forgot to put on, http://www.amazon.com/Garden-L..._hpc_img_z
My gosh that's alot of posts. This is the last one!

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written by patti , May 22, 2014
thank you so much for all the info .All the stories about c diff are almost exactly what im dealing with now . My mom has chf, caught it at a nursing home when she wentfor rehabilitation. she had pheumonia. Its a night mare, I am the one helping my mom. I have been researching all this info and comments. my mom is in the hosp right now. 2wks. third trip , She is 80, has had 2 valves replaced. I don't know how she is doing it. My fear is that she is being released tomorow. I dont want her going bk to her house before I find a way to kill these horrible spores. carpet -bleach or cut it out.. The probiotics are the first thing i'm buying tomorow. I know she wants out of hosp; but the test wont show if she will have a relapse.. Thank You again The family members have been visiting without protection. Should she stay in hospital ? Or back to her house after its been cleaned ? I wish i had found this page 3 days ago. How do I handle tomorow. I'm exhausted.Being Caretaker is not easy at all. I pray for everyone here that the suffering stops. Stop the suffering. I pray . Amen
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